A role for Grb2 in apoptosis?

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1995
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  • PMID https://pubmed.ncbi.nlm.nih.gov/17180072
  • OpenAlex ID W2419031090
  • Type Article
  • Language EN
  • Published 01 Apr 1995
  • Volume 2 (2)
  • Pages 105–11
  • Source PubMed
  • Publisher National Institutes of Health
  • FWCI 0.36
  • Added 10 Oct 2025
  • Updated 29 Sep 2026
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A role for Grb2 in apoptosis?

Article 1995 EN

Src homology type 2 (SH2) and type 3 (SH3) domains appear to have an important role in signal transduction pathways initiated by tyrosine kinases. SH2 domains allow proteins with signalling functions to interact with tyrosine kinases and tyrosine-phosphorylated proteins at the plasma membrane, whereas SH3 domains allow a distinct type of interaction through binding to proline-rich sequences. The a…

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6 authors
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1 I Rey — —
2 Isabelle Fath — —
3 Fabienne Parker — —
4 Fabian Haun — —
5 Fabien Schweighoffer — —
6 Bruno Tocqué — —

Data: OpenAlex