Abstract A163: Development of Grb2 SH3 domain antagonists

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2009
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  • DOI 10.1158/1535-7163.targ-09-a163
  • OpenAlex ID W2043201351
  • Type Conference-abstract
  • Language EN
  • Published 01 Dec 2009
  • Volume 8 (12_Supplement)
  • Pages A163
  • Source Molecular Cancer Therapeutics
  • Publisher American Association for Cancer Res…
  • Countries 1
  • Institutions 1
  • Added 10 Oct 2025
  • Updated 22 Sep 2026
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Abstract A163: Development of Grb2 SH3 domain antagonists

Conference-abstract 2009 EN

Abstract Src-homology 3 (SH3) domains are small modules of about 60 amino acids residues found in proteins that participate in many signaling pathways. As such, SH3 domains are involved in the regulation of several important cellular processes, including cell growth and differentiation, cell movement, protein trafficking and degradation, and immune responses. The adaptor protein Grb2 contains two…

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UN Sustainable Development Goals
1 SDGs
Authors & Affiliations
4 authors
#AuthorInstitutionsORCID
1 Alessio Giubellino National Cancer Institute (US)
2 Fa Liu National Cancer Institute (US)
3 Terrence R. Burke National Cancer Institute (US)
4 Donald Paul Bottaro National Cancer Institute (US)

Data: OpenAlex