Grb10 and Grb14: enigmatic regulators of insulin action – an…

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2005
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  • DOI 10.1042/bj20050216
  • PMID https://pubmed.ncbi.nlm.nih.gov/15901248
  • OpenAlex ID W2013246256
  • Type Article
  • Language EN
  • Published 24 May 2005
  • Volume 388 (2)
  • Pages 393–406
  • Source Biochemical Journal
  • Publisher Portland Press
  • FWCI 3.11
  • Countries 1
  • Institutions 2
  • Added 10 Oct 2025
  • Updated 12 Oct 2026
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Grb10 and Grb14: enigmatic regulators of insulin action – and more?

Article 2005 EN Bronze

The Grb proteins (growth factor receptor-bound proteins) Grb7, Grb10 and Grb14 constitute a family of structurally related multidomain adapters with diverse cellular functions. Grb10 and Grb14, in particular, have been implicated in the regulation of insulin receptor signalling, whereas Grb7 appears predominantly to be involved in focal adhesion kinase-mediated cell migration. However, at least in…

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1 Lowenna J. Holt University of Cambridge (GB) Addenbrooke's Hospital (GB)
2 Kenneth Siddle University of Cambridge (GB) Addenbrooke's Hospital (GB) —
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