TNF-α exacerbates cholesterol accumulation via down-regulati…
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- OpenAlex ID W2359040809
- Type Article
- Language EN
- Published 01 Jan 2013
- Source Zhongguo bingli shengli zazhi
- Publisher Chinese Medical Association
- FWCI 0.33
- Countries 1
- Institutions 1
- Added 24 Jun 2016
- Updated 24 Sep 2026
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TNF-α exacerbates cholesterol accumulation via down-regulating LXRα promoter activity in HepG2 cells
Article 2013 EN
AIM: To investigate the exacerbating effect of tumor necrosis factor alpha(TNF-α) on lipid accumulation in HepG2 cells by inhibiting liver X receptor alpha(LXRα) signaling pathway.METHODS: Luciferase reporter plasmid driven by the LXRα promoter(pGL3-Basic-LXRα-P) was constructed and transfected into HepG2 cells to detect the LXRα promoter activity.HepG2 cells were incubated with serum-free medium(…
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1 authors| # | Author | Institutions | ORCID |
|---|---|---|---|
| 1 | Yaxi Chen Corresponding | Chongqing Medical University (CN) |
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