Regulation of TNF-a in Monocytes by LXR and RXR
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- DOI 10.71548/5920
- OpenAlex ID W7115824755
- Type Dissertation
- Language EN
- Published 01 Aug 2002
- Source MacSphere (McMaster University)
- Publisher McMaster University
- Added 17 Dec 2025
- Updated 12 Oct 2026
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Regulation of TNF-a in Monocytes by LXR and RXR
Dissertation 2002 EN
Liver X receptor (LXR) is a member of the nuclear hormone receptor superfamily that is activated by hydroxylated cholesterol derivatives referred to as oxysterols. It has also been shown to play a crucial role in regulating cholesterol trafficking and lipid metabolism in liver and macrophages. Furthermore, LXR. has also been directly implicated in the reduction of atherosclerosis in several murine…
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1 SDGsAuthors & Affiliations
1 authors| # | Author | Institutions | ORCID |
|---|---|---|---|
| 1 | Landis, Mark Corresponding | — | — |
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