TNFα-Induced LDL Cholesterol Accumulation Involve Elevated L…
Established
23
Citations124
Refs2021
Year
Search Works
Work Details
- DOI 10.3390/ijms22126236
- PMID https://pubmed.ncbi.nlm.nih.gov/34207810
- PMCID https://www.ncbi.nlm.nih.gov/pmc/articles/8227244
- OpenAlex ID W3123402638
- Type Article
- Language EN
- Published 09 Jun 2021
- Volume 22 (12)
- Pages 6236
- Source International Journal of Molecular Scien…
- Publisher Multidisciplinary Digital Publishin…
- FWCI 2.60
- Countries 1
- Institutions 1
- Added 01 Feb 2021
- Updated 28 Oct 2026
External Links
MENU
0
TNFα-Induced LDL Cholesterol Accumulation Involve Elevated LDLR Cell Surface Levels and SR-B1 Downregulation in Human Arterial Endothelial Cells
Article 2021 EN Gold
ABSTRACT Excess lipid droplets are frequently observed in arterial endothelial cells at sites of advanced atherosclerotic plaques. Here, the role of tumor necrosis factor alpha (TNFα) in modulating low density lipoprotein (LDL) content in confluent primary human aortic endothelial cells (pHAECs) was investigated. TNFα promoted up to 2 folds increase in cellular cholesterol, which was resistant to…
23
Citations
124
References
1
Authors
2.60
FWCI
Citations by Year
Last 7 yearsTopics
Keywords
UN Sustainable Development Goals
1 SDGsAuthors & Affiliations
1 authors| # | Author | Institutions | ORCID |
|---|---|---|---|
| 1 | Emmanuel U. Okoro Corresponding | Meharry Medical College (US) |
Related Works
10Data: OpenAlex