Role of ERα and ERβ in oestrogen action in human breast canc…

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2007
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  • OpenAlex ID W7005827608
  • Type Dissertation
  • Language EN
  • Published 01 Jan 2007
  • Source OpenGrey (Institut de l'Information Scie…
  • Publisher Institut de l'Information Scientifi…
  • Added 10 Oct 2025
  • Updated 12 Oct 2026
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Role of ERα and ERβ in oestrogen action in human breast cancer cells

Dissertation 2007 EN

The role of ERα in hormone responsive breast cancer is well established but that of ERβ remains to be determined. In this thesis, the effects of overexpression of ERβlong have been studied in MCF7 human breast cancer cells which possess high endogenous levels of ERα . Stable overexpression of ERβlong protein (2-fold) resulted in reduced fold induction (from 2.6 to 1.8) of an ERE-CAT reporter gene…

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1 Dhamayanthi Pugazhendhi Corresponding —

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