Inducible upregulation of oestrogen receptor-β1 affects oest…

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2005
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  • DOI 10.1677/jme.1.01688
  • PMID https://pubmed.ncbi.nlm.nih.gov/15821116
  • OpenAlex ID W2118159105
  • Type Article
  • Language EN
  • Published 01 Apr 2005
  • Volume 34 (2)
  • Pages 553–566
  • Source Journal of Molecular Endocrinology
  • Publisher Bioscientifica
  • FWCI 3.40
  • Countries 1
  • Institutions 1
  • Added 24 Jun 2016
  • Updated 12 Oct 2026
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Inducible upregulation of oestrogen receptor-β1 affects oestrogen and tamoxifen responsiveness in MCF7 human breast cancer cells

Article 2005 EN Bronze

To investigate the effect of altered oestrogen receptor (ER)alpha and ERbeta expression on oestrogen and anti-oestrogen action in breast cancer, we have stably expressed an inducible ERbeta1 in MCF7 breast cancer cells. Stably expressing clones were isolated and over-expression of ERbeta1 correlated with increased levels of specific radiolabelled oestradiol (E2) binding. Increased ERbeta1 did not…

68

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67

References

9

Authors

3.40

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9 authors
#AuthorInstitutionsORCID
1 Leigh C. Murphy University of Manitoba (CA)
2 Baocheng Peng University of Manitoba (CA) —
3 AE Lewis University of Manitoba (CA) —
4 James Davie University of Manitoba (CA)
5 Etienne Leygue University of Manitoba (CA)
6 Angela Kemp University of Manitoba (CA) —
7 Kanyarat Ung University of Manitoba (CA) —
8 M Vendetti University of Manitoba (CA) —
9 Robert P. C. Shiu University of Manitoba (CA) —
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