Detection of an elevated HER2 expression in MCF-7 breast can…

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Detection of an elevated HER2 expression in MCF-7 breast cancer cells overexpressing estrogen receptor β1

Article 2008 EN Bronze

The estrogen receptor (ER) expression and HER2 amplification are important factors in determining the prognosis and therapy of breast cancer. Interactions between the two signaling pathways for example resulted in ERalpha-dependent regulation of HER2 expression in breast cancer cells. In this study, we investigated to what extent ERbeta is able to affect the HER2 expression. For this purpose, we a…

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4 authors
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1 Claus Lattrich University of Regensburg (DE) —
2 Ingolf Juhasz-Böess University of Regensburg (DE) —
3 Olaf Ortmann University of Regensburg (DE)
4 Oliver Treeck Corresponding Caritas-Krankenhaus St. Josef (DE) University of Regensburg (DE)

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