Inverse Regulation of EGFR/HER1 and HER2-4 in Normal and Mal…
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- DOI 10.1371/journal.pone.0074618
- PMID https://pubmed.ncbi.nlm.nih.gov/23991224
- PMCID https://www.ncbi.nlm.nih.gov/pmc/articles/3750010
- OpenAlex ID W1982646913
- Type Article
- Language EN
- Published 22 Aug 2013
- Volume 8 (8)
- Pages e74618
- Source PLoS ONE
- Publisher Public Library of Science
- FWCI 1.96
- Countries 2
- Institutions 3
- Added 24 Jun 2016
- Updated 30 Oct 2026
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Inverse Regulation of EGFR/HER1 and HER2-4 in Normal and Malignant Human Breast Tissue
Article 2013 EN Gold
Cross-talk between the estrogen and the EGFR/HER signalling pathways has been suggested as a potential cause of resistance to endocrine therapy in breast cancer. Here, we determined HER1-4 receptor and neuregulin-1 (NRG1) ligand mRNA expression levels in breast cancers and corresponding normal breast tissue from patients previously characterized for plasma and tissue estrogen levels. In tumours fr…
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63
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5
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1.96
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1 SDGsAuthors & Affiliations
5 authors| # | Author | Institutions | ORCID |
|---|---|---|---|
| 1 | Marianne Hauglid Flågeng | Haukeland University Hospital (NO) University of Bergen (NO) | — |
| 2 | Stian Knappskog | Haukeland University Hospital (NO) University of Bergen (NO) | |
| 3 | Ben P. Haynes | Royal Marsden Hospital (GB) | — |
| 4 | Per Eystein Lønning | Haukeland University Hospital (NO) University of Bergen (NO) | |
| 5 | Gunnar Mellgren Corresponding | Haukeland University Hospital (NO) University of Bergen (NO) |
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