Bimodal regulation of epidermal growth factor receptor by es…
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- DOI 10.1210/en.137.7.2739
- PMID https://pubmed.ncbi.nlm.nih.gov/8770893
- OpenAlex ID W2061471157
- Type Article
- Language EN
- Published 01 Jul 1996
- Volume 137 (7)
- Pages 2739–2747
- Source Endocrinology
- Publisher Oxford University Press
- FWCI 3.75
- Countries 1
- Institutions 3
- Added 24 Jun 2016
- Updated 27 Oct 2026
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Bimodal regulation of epidermal growth factor receptor by estrogen in breast cancer cells
Article 1996 EN
In breast cancer, epidermal growth factor (EGF) receptor (EGFR) expression is inversely correlated with expression of estrogen receptor (ER) and predicts the prognosis and failure of endocrine therapy. We report here, for the first time, that in ER-positive breast cancer cell lines, MCF-7, T47D, and BT474, 17 beta-estradiol (E2) transiently induced EGFR messenger RNA (mRNA) levels 2- to 3-fold; th…
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3.75
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1 SDGsAuthors & Affiliations
4 authors| # | Author | Institutions | ORCID |
|---|---|---|---|
| 1 | Ronit I. Yarden | Georgetown University (US) Georgetown Lombardi Comprehens… (US) | — |
| 2 | A H Lauber | Mayo Clinic (US) Georgetown University (US) +1 | — |
| 3 | Dorraya El‐Ashry | Georgetown University (US) Georgetown Lombardi Comprehens… (US) | |
| 4 | Susan A. Chrysogelos | Georgetown University (US) Georgetown Lombardi Comprehens… (US) | — |
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