Microbiota-derived I3A protects the intestine against radiat…
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- DOI 10.1080/19490976.2024.2347722
- PMID https://pubmed.ncbi.nlm.nih.gov/38706205
- PMCID https://www.ncbi.nlm.nih.gov/pmc/articles/11086037
- OpenAlex ID W4396664002
- Type Article
- Language EN
- Published 05 May 2024
- Volume 16 (1)
- Pages 2347722
- Source Gut Microbes
- Publisher Landes Bioscience
- FWCI 24.86
- Countries 1
- Institutions 3
- Added 07 May 2024
- Updated 31 Oct 2026
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Microbiota-derived I3A protects the intestine against radiation injury by activating AhR/IL-10/Wnt signaling and enhancing the abundance of probiotics
Article 2024 EN Gold
The intestine is prone to radiation damage in patients undergoing radiotherapy for pelvic tumors. However, there are currently no effective drugs available for the prevention or treatment of radiation-induced enteropathy (RIE). In this study, we aimed at investigating the impact of indole-3-carboxaldehyde (I3A) derived from the intestinal microbiota on RIE. Intestinal organoids were isolated and c…
98
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62
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7
Authors
24.86
FWCI
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UN Sustainable Development Goals
1 SDGsAuthors & Affiliations
7 authors| # | Author | Institutions | ORCID |
|---|---|---|---|
| 1 | Liwei Xie | Second Affiliated Hospital of … (CN) | |
| 2 | Shang Cai | Second Affiliated Hospital of … (CN) | |
| 3 | Hai-Yan Lu | Second Affiliated Hospital of … (CN) | — |
| 4 | Feng‐Ling Tang | Second Affiliated Hospital of … (CN) | |
| 5 | Ruiqiu Zhu | Second Affiliated Hospital of … (CN) | — |
| 6 | Ye Tian Corresponding | Second Affiliated Hospital of … (CN) | |
| 7 | Ming Li Corresponding | Soochow University (CN) State Key Laboratory of Radiat… (CN) |
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