Metformin alleviates irradiation-induced intestinal injury b…
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- DOI 10.3389/fmicb.2022.932294
- PMID https://pubmed.ncbi.nlm.nih.gov/36312920
- PMCID https://www.ncbi.nlm.nih.gov/pmc/articles/9608595
- OpenAlex ID W4304889748
- Type Article
- Language EN
- Published 13 Oct 2022
- Volume 13
- Pages 932294
- Source Frontiers in Microbiology
- Publisher Frontiers Media
- FWCI 2.42
- Countries 2
- Institutions 8
- Added 13 Oct 2022
- Updated 28 Oct 2026
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Metformin alleviates irradiation-induced intestinal injury by activation of FXR in intestinal epithelia
Article 2022 EN Gold
Abdominal irradiation (IR) destroys the intestinal mucosal barrier, leading to severe intestinal infection. There is an urgent need to find safe and effective treatments to reduce IR-induced intestinal injury. In this study, we reported that metformin protected mice from abdominal IR-induced intestinal injury by improving the composition and diversity of intestinal flora. The elimination of intest…
21
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52
References
15
Authors
2.42
FWCI
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UN Sustainable Development Goals
1 SDGsAuthors & Affiliations
15 authors| # | Author | Institutions | ORCID |
|---|---|---|---|
| 1 | Jing-Yu Yang | Henan University (CN) | |
| 2 | Mengjie Liu | Henan University (CN) | |
| 3 | Lin Li Lv | Guangzhou First People's Hospi… (CN) South China University of Tech… (CN) | |
| 4 | Jin-Rong Guo | Henan University (CN) | — |
| 5 | Kai-Yue He | Henan University (CN) | — |
| 6 | Hong Zhang | Henan University (CN) | |
| 7 | Keke Wang | Jiangsu Cancer Hospital (CN) Nanjing Medical University (CN) | |
| 8 | Cui-Yun Cui | Zhengzhou University (CN) Henan Provincial People's Hosp… (CN) | — |
| 9 | Beizhan Yan | Zhengzhou University (CN) Henan Provincial People's Hosp… (CN) | |
| 10 | Dandan Du | — | |
| 11 | Jinhua Wang | Jiangsu Cancer Hospital (CN) Nanjing Medical University (CN) | |
| 12 | Qiang Ding | University of Alabama at Birmi… (US) | — |
| 13 | Guo-Long Liu Corresponding | Guangzhou First People's Hospi… (CN) South China University of Tech… (CN) | — |
| 14 | Zhi–Xiang Xu Corresponding | Henan University (CN) University of Alabama at Birmi… (US) | |
| 15 | Yong‐Ping Jian Corresponding | Henan University (CN) |
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