1215 Using nanoparticles as artificial antigen presenting ce…

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  • DOI 10.1136/jitc-2023-sitc2023.1215
  • OpenAlex ID W4388076197
  • Type Conference-abstract
  • Language EN
  • Published 31 Oct 2023
  • Pages A1340
  • Source Regular and Young Investigator Award Abs…
  • Countries 1
  • Institutions 1
  • Added 01 Nov 2023
  • Updated 23 Aug 2026
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1215 Using nanoparticles as artificial antigen presenting cells to activate human CD4 T cells for immunotherapy

Conference-abstract 2023 EN Hybrid

Background CD4 T cells participate in anti-tumor immune responses, recruiting innate immune cells, direct lysis of tumor cells, and assisting CD8 activation. CD4 T cell-based adoptive cell transfer (ACT) therapies have clinical success across multiple cancer types, including metastatic melanoma and epithelial cancer.1 2 One of the challenges of CD4 T cell-based ACT therapy is finding methods to ex…

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UN Sustainable Development Goals
1 SDGs
Authors & Affiliations
3 authors
#AuthorInstitutionsORCID
1 Si-Sim Kang Johns Hopkins University (US)
2 Ariel Isser Johns Hopkins University (US)
3 Jonathan P. Schneck Johns Hopkins University (US)

Data: OpenAlex