CircRNA DICAR as a novel endogenous regulator for diabetic c…
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- DOI 10.1038/s41392-022-01306-2
- PMID https://pubmed.ncbi.nlm.nih.gov/36882410
- OpenAlex ID W4323535544
- Type Article
- Language EN
- Published 08 Mar 2023
- Volume 8 (1)
- Pages 99
- Source Signal Transduction and Targeted Therapy
- Publisher Springer Nature
- FWCI 8.95
- Countries 1
- Institutions 7
- Added 10 Oct 2025
- Updated 22 Oct 2026
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CircRNA DICAR as a novel endogenous regulator for diabetic cardiomyopathy and diabetic pyroptosis of cardiomyocytes
Article 2023 EN Gold
Abstract In this study, we identified that a conserved circular RNA (circRNA) DICAR, which was downregulated in diabetic mouse hearts. DICAR had an inhibitory effect on diabetic cardiomyopathy (DCM), as the spontaneous cardiac dysfunction, cardiac cell hypertrophy, and cardiac fibrosis occurred in DICAR deficiency (DICAR+/−) mice, whereas the DCM was alleviated in DICAR-overexpressed DICARTg mice.…
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1 SDGsAuthors & Affiliations
18 authors| # | Author | Institutions | ORCID |
|---|---|---|---|
| 1 | Qiong Yuan | Southwest Medical University (CN) Affiliated Hospital of Southwe… (CN) | |
| 2 | Yunwei Sun | Wuhan University of Science an… (CN) | — |
| 3 | Fan Yang | Guangdong Academy of Medical S… (CN) Guangdong Provincial People's … (CN) | |
| 4 | Dan Yan | Wuhan University of Science an… (CN) | — |
| 5 | Mei-Hua Shen | Wuhan University of Science an… (CN) | — |
| 6 | Zhigang Jin | Wuhan University of Science an… (CN) | — |
| 7 | Lin Zhan | Wuhan University of Science an… (CN) | |
| 8 | Guangqi Liu | Wuhan University of Science an… (CN) | |
| 9 | Ling Yang | Wuhan University of Science an… (CN) | |
| 10 | Qianyi Zhou | Wuhan University of Science an… (CN) | |
| 11 | Zhijun Yu | Wuhan University of Science an… (CN) | |
| 12 | Xiangyu Zhou | Southwest Medical University (CN) Affiliated Hospital of Southwe… (CN) | |
| 13 | Yang Yu | Southwest Medical University (CN) Affiliated Hospital of Southwe… (CN) | |
| 14 | Yong Xu | Southwest Medical University (CN) Affiliated Hospital of Southwe… (CN) | |
| 15 | Qingming Wu | Wuhan University of Science an… (CN) | |
| 16 | Jianfang Luo | Guangdong General Hospital (CN) | |
| 17 | Xiamin Hu Corresponding | Shanghai University of Medicin… (CN) | |
| 18 | Chunxiang Zhang Corresponding | Southwest Medical University (CN) Affiliated Hospital of Southwe… (CN) |
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