Cardioprotective Effect of Decorin in Type 2 Diabetes
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- DOI 10.3389/fendo.2020.479258
- PMID https://pubmed.ncbi.nlm.nih.gov/33365011
- OpenAlex ID W3111913477
- Type Article
- Language EN
- Published 07 Dec 2020
- Volume 11
- Pages 479258
- Source Frontiers in Endocrinology
- Publisher Frontiers Media
- FWCI 1.12
- Countries 1
- Institutions 4
- Added 10 Oct 2025
- Updated 16 Oct 2026
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Cardioprotective Effect of Decorin in Type 2 Diabetes
Article 2020 EN Gold
Cardiomyopathy is the leading cause of increased mortality in diabetes. In the present study, we investigated the effects of decorin (DCN) gene therapy on left ventricular function, cardiac inflammation and fibrosis in type 2 diabetes. Type 2 diabetes was induced in male Wistar rats by high fat diet (HFD, 60% of calories as fat) and STZ (20 mg/kg, intraperitoneal). Diabetic rats were divided into…
35
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36
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9
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1.12
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UN Sustainable Development Goals
1 SDGsAuthors & Affiliations
9 authors| # | Author | Institutions | ORCID |
|---|---|---|---|
| 1 | Fuqiong Chen | Tongji Hospital (CN) Huazhong University of Science… (CN) | — |
| 2 | Jinsheng Lai | Tongji Hospital (CN) Huazhong University of Science… (CN) | — |
| 3 | Yanfang Peipei Zhu | Wuhan University (CN) Zhongnan Hospital of Wuhan Uni… (CN) | |
| 4 | Mengying He | Tongji Hospital (CN) Huazhong University of Science… (CN) | — |
| 5 | Huiying Hou | Tongji Hospital (CN) Huazhong University of Science… (CN) | — |
| 6 | Jin Wang | Tongji Hospital (CN) Huazhong University of Science… (CN) | |
| 7 | Chen Chen | Tongji Hospital (CN) Huazhong University of Science… (CN) | |
| 8 | Dao Wen Wang Corresponding | Tongji Hospital (CN) Huazhong University of Science… (CN) | |
| 9 | Jiarong Tang Corresponding | Tongji Hospital (CN) Huazhong University of Science… (CN) | — |
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