Proteostasis and Ribostasis Impairment as Common Cell Death …

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Proteostasis and Ribostasis Impairment as Common Cell Death Mechanisms in Neurodegenerative Diseases

Review 2023 EN Diamond

The cellular homeostasis of proteins (proteostasis) and RNA metabolism (ribostasis) are essential for maintaining both the structure and function of the brain. However, aging, cellular stress conditions, and genetic contributions cause disturbances in proteostasis and ribostasis that lead to protein misfolding, insoluble aggregate deposition, and abnormal ribonucleoprotein granule dynamics. In add…

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147

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3

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UN Sustainable Development Goals
1 SDGs
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3 authors
#AuthorInstitutionsORCID
1 Su Min Lim Hanyang University (KR)
2 Minyeop Nahm Korea Brain Research Institute (KR)
3 Seung Hyun Kim Corresponding Hanyang University (KR)

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