Comparative genomic analyses of multiple backcross mouse pop…
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- DOI 10.1093/hmg/ddac150
- PMID https://pubmed.ncbi.nlm.nih.gov/35796564
- PMCID https://www.ncbi.nlm.nih.gov/pmc/articles/9703946
- OpenAlex ID W4284879953
- Type Article
- Language EN
- Published 07 Jul 2022
- Volume 31 (23)
- Pages 4019–4033
- Source Human Molecular Genetics
- Publisher Oxford University Press
- FWCI 0.75
- Countries 1
- Institutions 8
- Added 09 Jul 2022
- Updated 31 Oct 2026
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Comparative genomic analyses of multiple backcross mouse populations suggestSGCGas a novel potential obesity-modifier gene
Article 2022 EN Hybrid
To nominate novel disease genes for obesity and type 2 diabetes (T2D), we recently generated two mouse backcross populations of the T2D-susceptible New Zealand Obese (NZO/HI) mouse strain and two genetically different, lean and T2D-resistant strains, 129P2/OlaHsd and C3HeB/FeJ. Comparative linkage analysis of our two female backcross populations identified seven novel body fat-associated quantitat…
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15 authors| # | Author | Institutions | ORCID |
|---|---|---|---|
| 1 | Tanja Kuhn | Deutsches Diabetes-Zentrum e.V… (DE) German Center for Diabetes Res… (DE) +1 | — |
| 2 | Katharina Kaiser | Deutsches Diabetes-Zentrum e.V… (DE) German Center for Diabetes Res… (DE) +1 | — |
| 3 | Sandra Lebek | Deutsches Diabetes-Zentrum e.V… (DE) German Center for Diabetes Res… (DE) +1 | — |
| 4 | Delsi Altenhofen | Deutsches Diabetes-Zentrum e.V… (DE) German Center for Diabetes Res… (DE) +1 | |
| 5 | Birgit Knebel | Deutsches Diabetes-Zentrum e.V… (DE) German Center for Diabetes Res… (DE) +1 | |
| 6 | Ralf Herwig | Max Planck Institute for Molec… (DE) | |
| 7 | Axel Rasche | Max Planck Institute for Molec… (DE) | — |
| 8 | Angela Pelligra | Deutsches Diabetes-Zentrum e.V… (DE) German Center for Diabetes Res… (DE) +1 | |
| 9 | Sarah Görigk | Deutsches Diabetes-Zentrum e.V… (DE) German Center for Diabetes Res… (DE) +1 | — |
| 10 | Jenny Minh-An Khuong | Deutsches Diabetes-Zentrum e.V… (DE) German Center for Diabetes Res… (DE) +1 | — |
| 11 | Heike Vogel | German Center for Diabetes Res… (DE) German Institute of Human Nutr… (DE) | |
| 12 | Annette Schürmann | German Center for Diabetes Res… (DE) German Institute of Human Nutr… (DE) | |
| 13 | Matthias Blüher | Helmholtz Munich (DE) University Hospital Leipzig (DE) +1 | |
| 14 | Alexandra Chadt | Deutsches Diabetes-Zentrum e.V… (DE) German Center for Diabetes Res… (DE) +1 | |
| 15 | Hadi Al‐Hasani Corresponding | Deutsches Diabetes-Zentrum e.V… (DE) German Center for Diabetes Res… (DE) +1 |
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