Novel diabetes QTL on chromosomes 1, 9, 11 and 13 identified…

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  • DOI 10.1055/s-0034-1374968
  • OpenAlex ID W2320181564
  • Type Article
  • Language EN
  • Published 06 May 2014
  • Volume 9 (S 01)
  • Source Diabetologie und Stoffwechsel
  • Publisher Georg Thieme Verlag
  • Countries 1
  • Institutions 2
  • Added 24 Jun 2016
  • Updated 29 Sep 2026
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Novel diabetes QTL on chromosomes 1, 9, 11 and 13 identified in an NZOxC57BL/6J backcross population

Article 2014 EN

Background: The New Zealand Obese (NZO) mouse is a model for human polygenic obesity and type 2 diabetes. Outcross experiments with lean strains led to the discovery of various quantitative trait loci (QTL) and the subsequent identification of diabetes and obesity genes by positional cloning. The aim was to identify novel diabetes genes and suppressors in a backcross population of the NZO with the…

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UN Sustainable Development Goals
1 SDGs
Authors & Affiliations
9 authors
#AuthorInstitutionsORCID
1 Anne Kamitz German Institute of Human Nutr… (DE) —
2 Nicole Hallahan German Institute of Human Nutr… (DE)
3 R Burkhardt Leipzig University (DE) —
4 G. Schulze German Institute of Human Nutr… (DE) —
5 Markus Jähnert German Institute of Human Nutr… (DE)
6 Reinhard Kluge German Institute of Human Nutr… (DE) —
7 Wenke Jonas German Institute of Human Nutr… (DE)
8 Hans‐Georg Joost German Institute of Human Nutr… (DE)
9 Annette Schürmann German Institute of Human Nutr… (DE)

Data: OpenAlex