Nbw4 locus on mouse chromosome 4 harbors candidate genes whi…
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- DOI 10.1055/s-0043-1767886
- OpenAlex ID W4367674547
- Type Article
- Language EN
- Published 01 Apr 2023
- Volume 18 (S 01)
- Pages S22–S23
- Source Diabetologie und Stoffwechsel
- Publisher Georg Thieme Verlag
- Countries 1
- Institutions 2
- Added 03 May 2023
- Updated 12 Oct 2026
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Nbw4 locus on mouse chromosome 4 harbors candidate genes which protect from fat accumulation and obesity
Article 2023 EN
Background Obesity represents a major risk factor for the development of insulin resistance and T2D but the polygenic risk factors promoting obesity still remain to be identified. We conducted linkage analyses in a backcross population generated with T2D- prone New Zealand Obese (NZO) and lean C3HeB/FeJ mice and detected a quantitative trait locus on chromosome 4 (Nbw4) that conferred protection f…
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UN Sustainable Development Goals
1 SDGsAuthors & Affiliations
10 authors| # | Author | Institutions | ORCID |
|---|---|---|---|
| 1 | Jenny Minh-An Khuong | Deutsches Diabetes-Zentrum e.V… (DE) | — |
| 2 | Delsi Altenhofen | Deutsches Diabetes-Zentrum e.V… (DE) | |
| 3 | Mara Richter | Deutsches Diabetes-Zentrum e.V… (DE) | — |
| 4 | Tanja Kuhn | Deutsches Diabetes-Zentrum e.V… (DE) | — |
| 5 | Sandra Lebek | Deutsches Diabetes-Zentrum e.V… (DE) | — |
| 6 | Sarah Görigk | Deutsches Diabetes-Zentrum e.V… (DE) | — |
| 7 | Birgit Knebel | Deutsches Diabetes-Zentrum e.V… (DE) | |
| 8 | Annette Schürmann | German Institute of Human Nutr… (DE) | |
| 9 | Alexandra Chadt | Deutsches Diabetes-Zentrum e.V… (DE) | |
| 10 | Hadi Al‐Hasani | Deutsches Diabetes-Zentrum e.V… (DE) |
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