Specific NLRP3 Inflammasome Assembling and Regulation in Neu…
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- DOI 10.3390/cells11071188
- PMID https://pubmed.ncbi.nlm.nih.gov/35406754
- OpenAlex ID W4223565809
- Type Article
- Language EN
- Published 01 Apr 2022
- Volume 11 (7)
- Pages 1188
- Source Cells
- Publisher Multidisciplinary Digital Publishin…
- FWCI 3.52
- Countries 1
- Institutions 5
- Added 10 Oct 2025
- Updated 25 Oct 2026
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Specific NLRP3 Inflammasome Assembling and Regulation in Neutrophils: Relevance in Inflammatory and Infectious Diseases
Article 2022 EN Gold
The NLRP3 inflammasome is a cytosolic multimeric protein platform that leads to the activation of the protease zymogen, caspase-1 (CASP1). Inflammasome activation mediates the proteolytic activation of pro-inflammatory cytokines (IL-1β and IL-18) and program cell death called pyroptosis. The pyroptosis is mediated by the protein executioner Gasdermin D (GSDMD), which forms pores at the plasma memb…
66
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145
References
4
Authors
3.52
FWCI
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UN Sustainable Development Goals
1 SDGsAuthors & Affiliations
4 authors| # | Author | Institutions | ORCID |
|---|---|---|---|
| 1 | Christophe Paget Corresponding | Université de Tours (FR) Inserm (FR) +1 | |
| 2 | Emilie Doz | Université de Tours (FR) Institut National de Recherche… (FR) +1 | |
| 3 | Nathalie Winter | Université de Tours (FR) Institut National de Recherche… (FR) +1 | |
| 4 | Benoit Briard Corresponding | Université de Tours (FR) Inserm (FR) +1 |
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