Effect and mechanism of action of pine bark extract on glucose uptake by Caco‐2 cells

This work investigated the effect of pine bark extract (PBE) on glucose uptake by Caco‐2 cells. Cells were incubated in presence of PBE and [ 14 C] 3‐O‐methyl‐D‐glucose and the change in radioactivity of the incubation medium was measured. PBE reduced significantly glucose uptake but did affect neither the activity nor the expression of the Na + /K + ATPase suggesting that PBE affects the level of…