Role of Insulin Receptor in the Regulation of Glucose Uptake…
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- DOI 10.1210/en.2005-1663
- PMID https://pubmed.ncbi.nlm.nih.gov/16644916
- OpenAlex ID W2061301876
- Type Article
- Language EN
- Published 28 Apr 2006
- Volume 147 (8)
- Pages 3709–3718
- Source Endocrinology
- Publisher Oxford University Press
- FWCI 1.35
- Countries 1
- Institutions 2
- Added 10 Oct 2025
- Updated 08 Oct 2026
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Role of Insulin Receptor in the Regulation of Glucose Uptake in Neonatal Hepatocytes
Article 2006 EN Hybrid
The liver plays a major role in the regulation of glucose homoeostasis. Evidence from liver-specific insulin receptor knockout mice (LIRKO) suggested that insulin's direct and indirect effects on glucose utilization by the liver both require the presence of hepatic insulin receptors (IR). To address this issue, we have generated immortalized neonatal hepatocytes bearing (HIR LoxP) or not (HIR KO)…
66
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25
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3
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1.35
FWCI
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1 SDGsAuthors & Affiliations
3 authors| # | Author | Institutions | ORCID |
|---|---|---|---|
| 1 | Carmen Nevado | Universidad Complutense de Mad… (ES) Consejo Superior de Investigac… (ES) | — |
| 2 | Ángela M. Valverde Corresponding | Universidad Complutense de Mad… (ES) Consejo Superior de Investigac… (ES) | |
| 3 | Manuel Benito Corresponding | Universidad Complutense de Mad… (ES) Consejo Superior de Investigac… (ES) |
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