Regulation of Superoxide Anion Production by NADPH Oxidase i…
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- DOI 10.1161/01.atv.0000097769.47306.12
- PMID https://pubmed.ncbi.nlm.nih.gov/14525794
- OpenAlex ID W2147934559
- Type Article
- Language EN
- Published 07 Oct 2003
- Volume 24 (1)
- Pages 23–28
- Source Arteriosclerosis Thrombosis and Vascular…
- Publisher Lippincott Williams & Wilkins
- FWCI 5.51
- Countries 1
- Institutions 1
- Added 24 Jun 2016
- Updated 12 Oct 2026
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Regulation of Superoxide Anion Production by NADPH Oxidase in Monocytes/Macrophages
Article 2003 EN Bronze
Monocyte extravasation into the vessel wall has been shown to be a critical step in the development of atherosclerosis. Upon activation, monocytes produce a burst of superoxide anion due to activation of the NADPH oxidase enzyme complex. Monocyte-derived superoxide anion contributes to oxidant stress in inflammatory sites, is required for monocyte-mediated LDL oxidation, and alters basic cell func…
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1 authors| # | Author | Institutions | ORCID |
|---|---|---|---|
| 1 | Martha K. Cathcart Corresponding | Cleveland Clinic (US) | — |
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