Homocysteine stimulates phosphorylation of NADPH oxidase p47…

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95
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2006
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  • DOI 10.1042/bj20051810
  • PMID https://pubmed.ncbi.nlm.nih.gov/16626305
  • OpenAlex ID W1998791655
  • Type Article
  • Language EN
  • Published 27 Jul 2006
  • Volume 398 (1)
  • Pages 73–82
  • Source Biochemical Journal
  • Publisher Portland Press
  • FWCI 3.61
  • Countries 1
  • Institutions 2
  • Added 24 Jun 2016
  • Updated 14 Oct 2026
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Homocysteine stimulates phosphorylation of NADPH oxidase p47phoxand p67phoxsubunits in monocytes via protein kinase Cβ activation

Article 2006 EN Bronze

Hyperhomocysteinaemia is an independent risk factor for cardiovascular diseases due to atherosclerosis. The development of atherosclerosis involves reactive oxygen species-induced oxidative stress in vascular cells. Our previous study [Wang and O (2001) Biochem. J. 357, 233-240] demonstrated that Hcy (homocysteine) treatment caused a significant elevation of intracellular superoxide anion, leading…

95

Citations

37

References

4

Authors

3.61

FWCI

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4 authors
#AuthorInstitutionsORCID
1 Yaw Loong Siow St. Boniface Hospital (CA) University of Manitoba (CA)
2 Kathy K. W. Au-Yeung St. Boniface Hospital (CA) University of Manitoba (CA) —
3 Connie W. Woo St. Boniface Hospital (CA) University of Manitoba (CA)
4 O Karmin Corresponding St. Boniface Hospital (CA) University of Manitoba (CA)
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