Multiple Grb2-protein complexes in human cancer cells
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- DOI 10.1002/(sici)1097-0215(19970117)70:2<208::aid-ijc12>3.0.co;2-e
- PMID https://pubmed.ncbi.nlm.nih.gov/9009162
- OpenAlex ID W1981227239
- Type Article
- Language EN
- Published 17 Jan 1997
- Volume 70 (2)
- Pages 208–213
- Source International Journal of Cancer
- Publisher Wiley
- FWCI 0.56
- Countries 1
- Institutions 2
- Added 10 Oct 2025
- Updated 26 Oct 2026
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Multiple Grb2-protein complexes in human cancer cells
Article 1997 EN Bronze
Grb2 is an SH2/SH3 domain-containing adaptor protein that links receptor tyrosine kinases to the ras signaling pathway. The Grb2-SH2 domain binds phosphotyrosine sequences on activated tyrosine kinases, and one target of the SH3 domains is the ras-nucleotide-exchange factor Sos1. We have examined Grb2-protein interactions in human cancer cells that over-express the receptor tyrosine kinase erbB2.…
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UN Sustainable Development Goals
1 SDGsAuthors & Affiliations
3 authors| # | Author | Institutions | ORCID |
|---|---|---|---|
| 1 | Lakshmi Sastry Corresponding | Georgetown University Medical … (US) Georgetown Lombardi Comprehens… | |
| 2 | Tin M. Cao | Georgetown University Medical … (US) Georgetown Lombardi Comprehens… | — |
| 3 | C. Richter King | Georgetown University Medical … (US) Georgetown Lombardi Comprehens… |
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