Single‐Cell Dissection Reveals Immune Dysregulation After CD…
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- DOI 10.1002/advs.202509259
- PMID https://pubmed.ncbi.nlm.nih.gov/41290542
- PMCID https://www.ncbi.nlm.nih.gov/pmc/articles/12884813
- OpenAlex ID W4416670927
- Type Article
- Language EN
- Published 25 Nov 2025
- Volume 13 (8)
- Pages e09259
- Source Advanced Science
- Publisher Wiley
- FWCI 0.41
- Countries 1
- Institutions 4
- Added 27 Nov 2025
- Updated 31 Oct 2026
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Single‐Cell Dissection Reveals Immune Dysregulation After CD5 or CD7‐Directed Chimeric Antigen Receptor T‐Cell Therapy
Article 2025 EN Gold
CD5- and CD7-directed chimeric antigen receptor T-cell (5CAR and 7CAR) therapies for T-cell malignancies carry the risk of life-threatening infection. Although depletion of target-positive lymphocytes is expected, the contribution of residual cell dysfunction to infection risk remains unclear. This work uses single-cell sequencing to investigate immune dysregulation after 5CAR or 7CAR therapy in p…
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13
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0.41
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13 authors| # | Author | Institutions | ORCID |
|---|---|---|---|
| 1 | Yuechen Luo | Chinese Academy of Medical Sci… (CN) Institute of Hematology & Bloo… (CN) | — |
| 2 | Haixiao Zhang | Chinese Academy of Medical Sci… (CN) Institute of Hematology & Bloo… (CN) | — |
| 3 | Kaiting Tang | Chinese Academy of Medical Sci… (CN) Institute of Hematology & Bloo… (CN) | |
| 4 | Yiming Wang | — | |
| 5 | Huajiang Dong | — | — |
| 6 | Qi Wei | — | |
| 7 | Lingling Shan | Chinese Academy of Medical Sci… (CN) Institute of Hematology & Bloo… (CN) | — |
| 8 | Yue Tan | Chinese Academy of Medical Sci… (CN) Institute of Hematology & Bloo… (CN) | |
| 9 | Liping Zhao | Chinese Academy of Medical Sci… (CN) Institute of Hematology & Bloo… (CN) | |
| 10 | Jun Shi | Chinese Academy of Medical Sci… (CN) Institute of Hematology & Bloo… (CN) | — |
| 11 | Erlie Jiang Corresponding | Chinese Academy of Medical Sci… (CN) Institute of Hematology & Bloo… (CN) | |
| 12 | Jing Pan Corresponding | State Key Laboratory of Experi… (CN) | |
| 13 | Xiaoxue Feng Corresponding | Chinese Academy of Medical Sci… (CN) Institute of Hematology & Bloo… (CN) +1 |
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