Immune reconstitution after CD7 CAR ‐T cell therapy for refr…

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2025
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  • DOI 10.1111/bjh.70201
  • PMID https://pubmed.ncbi.nlm.nih.gov/41111252
  • OpenAlex ID W4415348129
  • Type Article
  • Language EN
  • Published 19 Oct 2025
  • Volume 208 (1)
  • Pages 229–238
  • Source British Journal of Haematology
  • Publisher Wiley
  • FWCI 0.41
  • Countries 1
  • Institutions 2
  • Added 20 Oct 2025
  • Updated 31 Oct 2026
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Immune reconstitution after CD7 CAR ‐T cell therapy for refractory/relapsed acute T‐lymphoblastic leukaemia/lymphoblastic lymphoma (R/R T‐ ALL / LBL )

Article 2025 EN

CD7 Chimeric Antigen Receptor-T cell (CAR-T) therapy demonstrates efficacy in relapsed/refractory (R/R) acute T-lymphoblastic leukaemia (ALL)T-ALL/lymphoblastic lymphoma (LBL), but concerns about T-cell depletion and severe immunodeficiency persist. We compared infection rates and immune cell subsets in 60 R/R T-ALL/LBL patients receiving naturally selected CD7 CAR-T (NS7CAR-T) with 60 R/R B-ALL p…

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1 SDGs
Authors & Affiliations
10 authors
#AuthorInstitutionsORCID
1 Xian Zhang Corresponding Beijing Dao Pei Hospital (CN) Hebei Yanda Ludaopei Hospital (CN)
2 Lin Wang —
3 Na Kuang — —
4 Junfang Yang Beijing Dao Pei Hospital (CN) Hebei Yanda Ludaopei Hospital (CN)
5 Hui Wang Beijing Dao Pei Hospital (CN) Hebei Yanda Ludaopei Hospital (CN)
6 Liyuan Qiu Beijing Dao Pei Hospital (CN) Hebei Yanda Ludaopei Hospital (CN) —
7 Dongchu Wang Beijing Dao Pei Hospital (CN) Hebei Yanda Ludaopei Hospital (CN) —
8 Jian Sun —
9 Jing Long Beijing Dao Pei Hospital (CN) Hebei Yanda Ludaopei Hospital (CN)
10 Peihua Lu Beijing Dao Pei Hospital (CN) Hebei Yanda Ludaopei Hospital (CN)

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