CD19-targeting CAR T cell therapy in five patients with syst…

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CD19-targeting CAR T cell therapy in five patients with systemic sclerosis unsuitable for autologous stem cell transplantation

Article 2025 EN Gold

Objectives: The efficacy of chimeric antigen receptor (CAR) T cell therapy in patients with systemic sclerosis (SSc) has been substantiated by a small number of case reports and series. An established treatment option for severe SSc is autologous stem cell transplantation (HSCT). The objective of this analysis was to assess the feasibility and safety of CD19-targeting CAR T cell therapy in patient…

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27

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7

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7 authors
#AuthorInstitutionsORCID
1 Ann‐Christin Pecher Universitätsklinikum Tübingen (DE)
2 Luca Hensen Universitätsklinikum Tübingen (DE)
3 Rebekka Schairer Universitätsklinikum Tübingen (DE)
4 Reinhild Klein Universitätsklinikum Tübingen (DE)
5 Wolfgang Andreas Bethge Universitätsklinikum Tübingen (DE)
6 Claudia Lengerke Universitätsklinikum Tübingen (DE)
7 Jörg Henes Corresponding Universitätsklinikum Tübingen (DE)

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