Safety and Efficacy of CD19 CAR-T Cells for Refractory Syste…
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- DOI 10.1182/blood-2022-169265
- OpenAlex ID W4310162925
- Type Article
- Language EN
- Published 15 Nov 2022
- Volume 140 (Supplement 1)
- Pages 10335–10336
- Source Blood
- Publisher Elsevier BV
- FWCI 2.72
- Countries 1
- Institutions 2
- Added 30 Nov 2022
- Updated 14 Oct 2026
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Safety and Efficacy of CD19 CAR-T Cells for Refractory Systemic Sclerosis: A Phase I Clinical Trial
Article 2022 EN
Background: Systemic sclerosis is a connective tissue disease characterized by multi-organ fibrosis, with B-cell dysfunction and antibody deposition as important causative factors and a poor prognosis. Although drugs or therapeutic approaches including CD20 monoclonal antibodies and autologous stem cell transplantation have shown some efficacy in treating this disease, there remains a significant…
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1 SDGsAuthors & Affiliations
12 authors| # | Author | Institutions | ORCID |
|---|---|---|---|
| 1 | Jingjing Feng | First Affiliated Hospital Zhej… (CN) | |
| 2 | Yongxian Hu | First Affiliated Hospital Zhej… (CN) | |
| 3 | Mingming Zhang | — | — |
| 4 | Heng Cao | First Affiliated Hospital Zhej… (CN) Zhejiang University (CN) | — |
| 5 | Yini Ke | First Affiliated Hospital Zhej… (CN) Zhejiang University (CN) | |
| 6 | Huijun Xu | First Affiliated Hospital Zhej… (CN) | |
| 7 | Jiazhen Cui | First Affiliated Hospital Zhej… (CN) | — |
| 8 | Yanlei Zhang | — | |
| 9 | Alex H. Chang | — | |
| 10 | Jin Lin | First Affiliated Hospital Zhej… (CN) Zhejiang University (CN) | |
| 11 | Guoqing Wei | First Affiliated Hospital Zhej… (CN) | — |
| 12 | He Huang | First Affiliated Hospital Zhej… (CN) |
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