Amyloidosis Inhibition and Detection of Human Islet Amyloid Polypeptide with Nanomaterials

Type 2 diabetes (T2D), a metabolic disorder that is associated with progressive β-cell failure, manifests as a decline in insulin secretion and increasing hyperglycemia. A growing body of evidence suggests that β-cell failure in T2D correlates with the formation of pancreatic islet amyloid deposits, indicating that islet amyloid may have an important role in β-cell loss in this disease. Islet amyl…