LRR-protein RNH1 dampens the inflammasome activation and is …
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- DOI 10.26508/lsa.202101226
- PMID https://pubmed.ncbi.nlm.nih.gov/35256513
- OpenAlex ID W4220994709
- Type Article
- Language EN
- Published 07 Mar 2022
- Volume 5 (6)
- Pages e202101226
- Source Life Science Alliance
- FWCI 1.04
- Countries 2
- Institutions 5
- Added 10 Oct 2025
- Updated 16 Oct 2026
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LRR-protein RNH1 dampens the inflammasome activation and is associated with COVID-19 severity
Article 2022 EN Gold
Inflammasomes are cytosolic innate immune sensors of pathogen infection and cellular damage that induce caspase-1–mediated inflammation upon activation. Although inflammation is protective, uncontrolled excessive inflammation can cause inflammatory diseases and can be detrimental, such as in coronavirus disease (COVID-19). However, the underlying mechanisms that control inflammasome activation are…
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1 SDGsAuthors & Affiliations
20 authors| # | Author | Institutions | ORCID |
|---|---|---|---|
| 1 | Giuseppe Bombaci | University of Bern (CH) University Hospital of Bern (CH) | |
| 2 | Mayuresh Anant Sarangdhar | University of Bern (CH) University Hospital of Bern (CH) | |
| 3 | Nicola Daniele Andina | University of Bern (CH) University Hospital of Bern (CH) | |
| 4 | Aubry Tardivel | University of Bern (CH) University Hospital of Bern (CH) | |
| 5 | Eric Chi-Wang Yu | University of Lausanne (CH) | |
| 6 | Gillian M. Mackie | University of Birmingham (GB) | |
| 7 | Matthew Pugh | University of Birmingham (GB) | |
| 8 | Vedat Burak Ozan | University of Bern (CH) University Hospital of Bern (CH) | |
| 9 | Yara Banz | University of Bern (CH) | |
| 10 | Thibaud Spinetti | University of Bern (CH) University Hospital of Bern (CH) | |
| 11 | Cédric Hirzel | University of Bern (CH) University Hospital of Bern (CH) | |
| 12 | Esther Youd | University of Glasgow (GB) | — |
| 13 | Joerg C. Schefold | University of Bern (CH) University Hospital of Bern (CH) | |
| 14 | Graham S. Taylor | University of Birmingham (GB) | |
| 15 | Amiq Gazdhar | University of Bern (CH) University Hospital of Bern (CH) | |
| 16 | Nicolas Bonadies | University of Bern (CH) University Hospital of Bern (CH) | |
| 17 | Anne Angelillo‐Scherrer | University of Bern (CH) University Hospital of Bern (CH) | |
| 18 | Pascal Schneider | University of Lausanne (CH) | |
| 19 | Kendle M. Maslowski | University of Birmingham (GB) | |
| 20 | Ramanjaneyulu Allam Corresponding | University of Bern (CH) University Hospital of Bern (CH) |
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