Curcumin Targets Both Apoptosis and Necroptosis in Acidity‐T…

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Curcumin Targets Both Apoptosis and Necroptosis in Acidity‐Tolerant Prostate Carcinoma Cells

Article 2021 EN Hybrid

OBJECTIVE: , is known to have anticancer potential and is still under investigation. In this study, we investigated the cytotoxic mechanism(s) of curcumin against acidity-tolerant prostate cancer PC-3AcT cells in lactic acid-containing medium. METHODS: Using 2D-monolyer and 3D spheroid culture models, MTT assay, annexin V-PE binding assay, flow cytometric analysis, measurement of ATP content, and…

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3 authors
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1 Yoon‐Jin Lee Soonchunhyang University (KR)
2 Kwan-Sik Park Soonchunhyang University (KR) —
3 Sang-Han Lee Corresponding Soonchunhyang University (KR)

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