Chlorogenic Acid Alleviates Hyperglycemia‐Induced Cardiac Fi…

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Chlorogenic Acid Alleviates Hyperglycemia‐Induced Cardiac Fibrosis through Activation of the NO/cGMP/PKG Pathway in Cardiac Fibroblasts

Article 2020 EN

SCOPE: Hyperglycemia-induced cardiac fibrosis is one of the main causes of diabetic cardiomyopathy (DM). Chlorogenic acid (CGA) found in many foods has excellent hypoglycemic effectiveness, but it is not known whether CGA can improve DM by inhibiting cardiac fibrosis caused by hyperglycemia. METHODS AND RESULTS: Type I diabetic mice are induced by streptozotocin, and after treatment with CGA for 1…

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7 authors
#AuthorInstitutionsORCID
1 Linhui Qin Zhengzhou University (CN)
2 Ming‐Xi Zang Zhengzhou University (CN)
3 Yan Chun Xu Zhengzhou University (CN)
4 Rongrong Zhao Zhengzhou University (CN)
5 Yating Wang Zhengzhou University (CN)
6 Yang Mi Zhengzhou University (CN)
7 Yingwu Mei Corresponding Zhengzhou University (CN)

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