2-Arachidonoylglycerol Attenuates Myocardial Fibrosis in Dia…

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2022
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  • DOI 10.1007/s10557-021-07307-7
  • PMID https://pubmed.ncbi.nlm.nih.gov/35305183
  • OpenAlex ID W4221003133
  • Type Article
  • Language EN
  • Published 19 Mar 2022
  • Volume 37 (4)
  • Pages 647–654
  • Source Cardiovascular Drugs and Therapy
  • Publisher Springer Science+Business Media
  • FWCI 1.24
  • Countries 1
  • Institutions 2
  • Added 10 Oct 2025
  • Updated 16 Oct 2026
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2-Arachidonoylglycerol Attenuates Myocardial Fibrosis in Diabetic Mice Via the TGF-β1/Smad Pathway

Article 2022 EN Hybrid

PURPOSE: Diabetic cardiomyopathy (DM) is the cause of late cardiac dysfunction in diabetic patients. Myocardial fibrosis is the main pathological mechanism, and it is associated with transforming growth factor-β1(TGF-β1) expression up-regulation. 2-Arachidonoylglycerol (2-AG) is an endogenous cannabinoid that can effectively improve myocardial cell energy metabolism and cardiac function. Here, we…

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1 Zhengjie Chen Sir Run Run Shaw Hospital (CN) Zhejiang University (CN)
2 Liangyu Zheng Sir Run Run Shaw Hospital (CN) Zhejiang University (CN) —
3 Gang Chen Corresponding Sir Run Run Shaw Hospital (CN) Zhejiang University (CN)
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