GMP-Compliant Manufacturing of NKG2D CAR Memory T Cells Usin…
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- DOI 10.3389/fimmu.2019.02361
- PMID https://pubmed.ncbi.nlm.nih.gov/31649672
- PMCID https://www.ncbi.nlm.nih.gov/pmc/articles/6795760
- OpenAlex ID W2979872362
- Type Article
- Language EN
- Published 10 Oct 2019
- Volume 10
- Pages 2361
- Source Frontiers in Immunology
- Publisher Frontiers Media
- FWCI 3.65
- Countries 1
- Institutions 4
- Added 18 Oct 2019
- Updated 31 Oct 2026
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GMP-Compliant Manufacturing of NKG2D CAR Memory T Cells Using CliniMACS Prodigy
Article 2019 EN Gold
NKG2D is a NK cell activating receptor that recognizes different stress-induced ligands that are overexpressed in a variety of childhood and adult tumors. NKG2D CAR T cells have shown potent anticancer effects against different cancer types. A second-generation NKG2D CAR was generated by fusing full-length human NKG2D to 41BB costimulatory molecule and CD3ζ signaling domain. Patient-derived CAR T…
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1 SDGsAuthors & Affiliations
14 authors| # | Author | Institutions | ORCID |
|---|---|---|---|
| 1 | Lucía Fernández Corresponding | Spanish National Cancer Resear… (ES) | |
| 2 | Adrián Fernández | Spanish National Cancer Resear… (ES) | |
| 3 | Isabel Mirones | Hospital Universitario La Paz (ES) Hospital La Paz Institute for … (ES) | |
| 4 | Adela Escudero | Hospital Universitario La Paz (ES) | |
| 5 | Leila Cabral de Almeida Cardoso | Hospital Universitario La Paz (ES) | |
| 6 | María Vela | Hospital Universitario La Paz (ES) Hospital La Paz Institute for … (ES) | |
| 7 | Diego Lanzarot | — | — |
| 8 | Raquel de Paz | Hospital Universitario La Paz (ES) | |
| 9 | Alejandra Leivas | Spanish National Cancer Resear… (ES) Hospital Universitario 12 De O… (ES) | |
| 10 | Miguel Gallardo | Spanish National Cancer Resear… (ES) Hospital Universitario 12 De O… (ES) | |
| 11 | Antônio Marcos | Hospital Universitario La Paz (ES) | — |
| 12 | Ana Belén Romero | Hospital Universitario La Paz (ES) | — |
| 13 | Joaquín Martínez‐López | Spanish National Cancer Resear… (ES) Hospital Universitario 12 De O… (ES) | |
| 14 | Antonio Pérez‐Martínez Corresponding | Hospital Universitario La Paz (ES) Hospital La Paz Institute for … (ES) |
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