Automated Manufacturing of Potent CD20-Directed Chimeric Ant…
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- DOI 10.1089/hum.2017.111
- PMID https://pubmed.ncbi.nlm.nih.gov/28847167
- OpenAlex ID W2761560083
- Type Article
- Language EN
- Published 29 Aug 2017
- Volume 28 (10)
- Pages 914–925
- Source Human Gene Therapy
- Publisher Mary Ann Liebert, Inc.
- FWCI 5.43
- Countries 1
- Institutions 2
- Added 20 Oct 2017
- Updated 31 Oct 2026
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Automated Manufacturing of Potent CD20-Directed Chimeric Antigen Receptor T Cells for Clinical Use
Article 2017 EN Hybrid
The clinical success of gene-engineered T cells expressing a chimeric antigen receptor (CAR), as manifested in several clinical trials for the treatment of B cell malignancies, warrants the development of a simple and robust manufacturing procedure capable of reducing to a minimum the challenges associated with its complexity. Conventional protocols comprise many open handling steps, are labor int…
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15
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5.43
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1 SDGsAuthors & Affiliations
15 authors| # | Author | Institutions | ORCID |
|---|---|---|---|
| 1 | Dominik Lock | Miltenyi Biotec (Germany) (DE) | |
| 2 | Nadine Mockel-Tenbrinck | Miltenyi Biotec (Germany) (DE) | — |
| 3 | Katharina Drechsel | Miltenyi Biotec (Germany) (DE) | — |
| 4 | Carola Barth | Miltenyi Biotec (Germany) (DE) | — |
| 5 | Daniela Mauer | Miltenyi Biotec (Germany) (DE) | |
| 6 | Thomas Schaser | Miltenyi Biotec (Germany) (DE) | |
| 7 | Carolin Kolbe | Miltenyi Biotec (Germany) (DE) | — |
| 8 | Wa’el Al Rawashdeh | Miltenyi Biotec (Germany) (DE) | — |
| 9 | Janina Brauner | Miltenyi Biotec (Germany) (DE) | — |
| 10 | Olaf Hardt | Miltenyi Biotec (Germany) (DE) | |
| 11 | Natali Pflug | University Hospital Cologne (DE) | |
| 12 | Udo Holtick | University Hospital Cologne (DE) | |
| 13 | Peter Borchmann | University Hospital Cologne (DE) | |
| 14 | Mario Assenmacher | Miltenyi Biotec (Germany) (DE) | — |
| 15 | Andrew Kaiser | Miltenyi Biotec (Germany) (DE) | — |
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