Hypothalamic PDE3B deficiency alters body weight and glucose…
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- DOI 10.1530/joe-18-0304
- PMID https://pubmed.ncbi.nlm.nih.gov/30307157
- OpenAlex ID W2895670063
- Type Article
- Language EN
- Published 01 Oct 2018
- Volume 239 (1)
- Pages 93–105
- Source Journal of Endocrinology
- Publisher Bioscientifica
- FWCI 0.12
- Countries 1
- Institutions 2
- Added 10 Oct 2025
- Updated 01 Sep 2026
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Hypothalamic PDE3B deficiency alters body weight and glucose homeostasis in mouse
Article 2018 EN Green
Pharmacological studies have suggested hypothalamic phosphodiesterase-3B to mediate leptin and insulin action in regulation of energy homeostasis. Whereas Pde3b-null mice show altered energy homeostasis, it is unknown whether this is due to ablation of Pde3b in the hypothalamus. Thus, to address the functional significance of hypothalamic phosphodiesterase-3B, we used Pde3bflox/flox and Nkx2.1-Cre…
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1 SDGsAuthors & Affiliations
3 authors| # | Author | Institutions | ORCID |
|---|---|---|---|
| 1 | Maitrayee Sahu | University of Pittsburgh (US) Magee-Womens Research Institut… (US) | — |
| 2 | Prashanth Anamthathmakula | University of Pittsburgh (US) Magee-Womens Research Institut… (US) | |
| 3 | Abhiram Sahu | University of Pittsburgh (US) Magee-Womens Research Institut… (US) | — |
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