Hypothalamic Proopiomelanocortin Is Necessary for Normal Glu…

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Hypothalamic Proopiomelanocortin Is Necessary for Normal Glucose Homeostasis in Female Mice

Article 2018 EN Gold

The arcuate nucleus of the hypothalamus is a key regulator of energy balance and glucose homeostasis. In particular, arcuate proopiomelanocortin (POMC) neurons inhibit food intake, stimulate energy expenditure and increase glucose tolerance. The interruption of insulin or glucose signaling in POMC neurons leads to glucose intolerance without changing energy homeostasis. Although it was previously…

9

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28

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3

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0.34

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3 authors
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1 Ramiro Alsina Consejo Nacional de Investigac… (AR) Universidad de Buenos Aires (AR) —
2 Milagros Trotta Consejo Nacional de Investigac… (AR) Universidad de Buenos Aires (AR) —
3 Viviana Florencia Bumaschny Corresponding Consejo Nacional de Investigac… (AR) Universidad de Buenos Aires (AR)

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