Synthesis of 3-((4-(1H-imidazo[4,5-b]pyridin-2-yl)phenyl)met…

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  • OpenAlex ID W2582013189
  • Type Article
  • Language EN
  • Published 01 Jan 2014
  • Volume 6 (5)
  • Pages 84–87
  • Source Der pharma chemica
  • Added 03 Feb 2017
  • Updated 29 Sep 2026
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Synthesis of 3-((4-(1H-imidazo[4,5-b]pyridin-2-yl)phenyl)methylamino)-2-arylthiazolidin-4-ones and 4-(1H-imidazo[4,5-b]pyridin-2-yl)phenyl)-N-(5-aryl-1H-1,2,3-triazol-1-yl)methanamines

Article 2014 EN

2-(chloromethyl)-1H-imidazo[4,5-b]pyridinereacts with hydrazine to form 1-((1H-imidazo[4,5-b]pyridin-2- yl)methyl)hydrazine (2), which on condensation with aromatic aldehydes converts in to 1-((4-(1H-imidazo[4,5- b]pyridin-2-yl)phenyl)methyl)-2-arylidenehydrazines (3a-f). Compounds 3a-f on reaction with thioglycolic acid and diazomethane lead to form 3-((4-(1H-imidazo[4,5-b]pyridin-2-yl)phenyl)met…

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3 authors
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1 Ramakrishnan Ajay Kumar —
2 Dayakar Govindu — —
3 I Sujatha — —

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