Pharmaceutical Studies on Hydrates of AM-715 : Physical Char…

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Pharmaceutical Studies on Hydrates of AM-715 : Physical Characteristics and Intestinal Absorption

Article 1982 EN Bronze

The presence of three kinds of hydrates of AM-715 (1-ethyl-6-fluoro-1, 4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid) was confirmed by elemental analysis, Karl-Fischer method, thermogravimetric analysis, differential scanning calorimetry, infrared spectroscopy, and X-ray diffractometry. Anhydrous AM-715 was not hygroscopic under less than 36% of relative humidity, but easily transfo…

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6 authors
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1 Ryuzo Yuasa — —
2 Jun Imai —
3 Hiroshi Morikawa —
4 Hisao Kusajima — —
5 Hiroshi Uchida —
6 Tsutomu Irikura — —

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