Single enantiomer drugs: should they be developed?
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- PMID https://pubmed.ncbi.nlm.nih.gov/16989289
- OpenAlex ID W2411637668
- Type Article
- Language EN
- Published 01 Jan 2006
- Volume 7 (1)
- Pages 15–23
- Source PubMed
- Publisher National Institutes of Health
- FWCI 0.15
- Countries 1
- Institutions 1
- Added 10 Oct 2025
- Updated 22 Sep 2026
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Single enantiomer drugs: should they be developed?
Article 2006 EN
Biological interactions are stereoselective; thus the interactions of drugs with corresponding biological targets must also be stereoselective. However, many drugs used today are racemic mixtures. For example, approximately 25% or 1 in 4 marketed drugs are mixtures of agents (racemates) rather than single chemical entities (enantiomers). One of these enantiomers can be inactive or even counterprod…
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UN Sustainable Development Goals
1 SDGsAuthors & Affiliations
3 authors| # | Author | Institutions | ORCID |
|---|---|---|---|
| 1 | Ahsan Yaqoob Khan | University of Kansas (US) | — |
| 2 | Sheldon Preskorn | — | — |
| 3 | Kandatege Wimalasena | — |
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