RACEMATES OR ENANTIOMERS: REGULATORY APPROACHES

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1989
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RACEMATES OR ENANTIOMERS: REGULATORY APPROACHES

Article 1989 EN

1. Racemic drugs contain enantiomers which can differ substantially in pharmacological and dispositional properties. The development of chemical methods to separate and analyse drug enantiomers has led to a growing understanding of their biological properties and a regulatory dilemma as to whether only enantiomerically pure drugs should be marketed. 2. Advantages of enantiomerically pure drugs inc…

29

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11

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1

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1.63

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1 Donald Birkett Corresponding Flinders University (AU) Flinders Medical Centre (AU) —

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