Expression of the hBD-2 and change of NF-κB activity in human primary epitheliums induced by LPS

AIM:To investigate the expression of human β-defensin-2(hBD-2)mRNA and the changes of NF-κB activity induced by lipopolysaccharide(LPS)in human primary epitheliums.METHODS:The pulmonary primary epitheliums from human were stimulated with LPS and the expression of hBD-2 mRNA was detected by reverse transcription polymerase chain reaction(RT-PCR).The nuclear factor-kappa B(NF-κB)binding activity was…