Impaired gastric acid secretion in gastrin-deficient mice

Well Cited

208
Citations
37
Refs
1998
Year
Search Works
Work Details
  • DOI 10.1152/ajpgi.1998.274.3.g561
  • PMID https://pubmed.ncbi.nlm.nih.gov/9530158
  • OpenAlex ID W2148023044
  • Type Article
  • Language EN
  • Published 01 Mar 1998
  • Volume 274 (3)
  • Pages G561–G568
  • Source American Journal of Physiology-Gastroint…
  • Publisher American Physiological Society
  • FWCI 4.18
  • Countries 3
  • Institutions 3
  • Added 24 Jun 2016
  • Updated 27 Oct 2026
External Links
OpenAlex Record DOI Resolver PubMed
MENU
0

Impaired gastric acid secretion in gastrin-deficient mice

Article 1998 EN

To further understand the role of the peptide hormone gastrin in the development and function of the stomach, we have generated gastrin-deficient mice by gene targeting in embryonic stem cells. Mutant mice were viable and fertile, without obvious visible abnormalities. However, gastric function was severely affected by the loss of gastrin. Basal gastric acid secretion was abolished and could not b…

208

Citations

37

References

9

Authors

4.18

FWCI

Citations by Year
Last 14 years
Topics
Keywords
UN Sustainable Development Goals
1 SDGs
Authors & Affiliations
9 authors
#AuthorInstitutionsORCID
1 Lennart Jan Friis-Hansen Rigshospitalet (DK)
2 F. Sundler Lund University (SE) —
3 Ying Li —
4 Patrick J. Gillespie — —
5 Thomas L. Saunders —
6 Joel K. Greenson University of Michigan (US)
7 Chung Owyang —
8 Jens Frederik Rehfeld Rigshospitalet (DK)
9 Linda C. Samuelson —
Related Works
10

Data: OpenAlex