Altered Expression of Hepatic CYP1A Enzymes in Rat Hepatocar…
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- DOI 10.1111/j.1349-7006.1995.tb02431.x
- PMID https://pubmed.ncbi.nlm.nih.gov/7622417
- PMCID https://www.ncbi.nlm.nih.gov/pmc/articles/5920875
- OpenAlex ID W2138385035
- Type Article
- Language EN
- Published 01 Jun 1995
- Volume 86 (6)
- Pages 535–539
- Source Japanese Journal of Cancer Research
- Publisher Oxford University Press
- FWCI 1.10
- Countries 1
- Institutions 1
- Added 24 Jun 2016
- Updated 28 Oct 2026
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Altered Expression of Hepatic CYP1A Enzymes in Rat Hepatocarcinogenesis
Article 1995 EN Green
Hyperplastic nodules of the liver were induced by treating male F344 rats with a combination of diethylnitrosamine and partial hepatectomy. The livers were examined for the expression of cytochrome P450 (CYP) enzymes, mainly CYP1A1 and CYP1A2; the amount and activity of the enzymes in the microsomes were assessed by enzymatic and immunological methods. Levels of CYP1A mRNAs were assayed by Norther…
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27
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1 SDGsAuthors & Affiliations
4 authors| # | Author | Institutions | ORCID |
|---|---|---|---|
| 1 | Masakuni Degawa Corresponding | Tohoku University (JP) | — |
| 2 | Shin‐ichi Miura | Tohoku University (JP) | |
| 3 | Kouichi Yoshinari | Tohoku University (JP) | |
| 4 | Yoshiyuki Hashimoto | Tohoku University (JP) | — |
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