Regulation and expression of four cytochrome P-450 isoenzyme…
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- DOI 10.1093/carcin/6.4.513
- PMID https://pubmed.ncbi.nlm.nih.gov/3921270
- OpenAlex ID W2014398730
- Type Article
- Language EN
- Published 01 Jan 1985
- Volume 6 (4)
- Pages 513–521
- Source Carcinogenesis
- Publisher Oxford University Press
- FWCI 13.59
- Countries 1
- Institutions 2
- Added 24 Jun 2016
- Updated 05 Oct 2026
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Regulation and expression of four cytochrome P-450 isoenzymes, NADPH-cytochrome P-450 reductase, the glutathione transferases B and C and microsomal epoxide hydrolase in preneoplastic and neoplastic lesions in rat liver
Article 1985 EN
Nitrosamine-induced hepatocarcinogenesis has been used to investigate the regulation and expression of different drug-metabolizing enzymes in preneoplastic and neoplastic lesions in the female Wistar rat. The enzymes investigated were two phenobarbital-inducible cytochrome P-450 (cyt. P-450) isoenzymes (PB1 and PB2, mol. wt. 52 000 and 53 500, respectively), two 3-methylcholanthrene-inducible form…
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13.59
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1 SDGsAuthors & Affiliations
8 authors| # | Author | Institutions | ORCID |
|---|---|---|---|
| 1 | Albrecht Buchmann | German Cancer Research Center (DE) | — |
| 2 | Wolf Dieter Kuhlmann | German Cancer Research Center (DE) | — |
| 3 | Markus Schwarz | German Cancer Research Center (DE) | |
| 4 | W. Kunz | German Cancer Research Center (DE) | — |
| 5 | C. Roland Wolf | — | |
| 6 | E. Moll | Johannes Gutenberg University … (DE) | — |
| 7 | Thomas Friedberg | Johannes Gutenberg University … (DE) | — |
| 8 | Franz Oesch | Johannes Gutenberg University … (DE) |
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