Calcium channels for endocytosis

Exocytosis and endocytosis need to be tightly balanced to keep cell surface area constant. This is of particular relevance for presynaptic terminals, where endocytosis needs to compensate for the ongoing exocytosis of synaptic vesicle to ultimately guarantee reliable synaptic transmission. How the endocytotic machinery manages to balance exocytosis is poorly understood. In principle, several mecha…