Estrogen Up-regulates ATBF1 Transcription but Causes Its Pro…

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Estrogen Up-regulates ATBF1 Transcription but Causes Its Protein Degradation in Estrogen Receptor-α-positive Breast Cancer Cells

Article 2011 EN Hybrid

The proper level of estrogen-estrogen receptor (ER) signaling is important for the maintenance of epithelial homeostasis in the breast. In a previous study we demonstrated that ATBF1, which has been suggested as a tumor suppressor in breast cancer, inhibited estrogen-mediated cell proliferation by selectively competing with AIB1 for binding to the ER. However, the expression of ATBF1 mRNA was show…

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5 authors
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1 Xue–Yuan Dong Corresponding Emory University (US) Winship Cancer Institute (US)
2 Peng Guo Emory University (US) Winship Cancer Institute (US)
3 Xiaodong Sun Emory University (US) Winship Cancer Institute (US) —
4 Qunna Li Emory University (US) Winship Cancer Institute (US)
5 Jin‐Tang Dong Corresponding Emory University (US) Winship Cancer Institute (US)

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