Comparison of Sequencing Platforms for Single Nucleotide Var…
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- DOI 10.1371/journal.pone.0055089
- PMID https://pubmed.ncbi.nlm.nih.gov/23405114
- OpenAlex ID W2073445420
- Type Article
- Language EN
- Published 06 Feb 2013
- Volume 8 (2)
- Pages e55089
- Source PLoS ONE
- Publisher Public Library of Science
- FWCI 8.31
- Countries 1
- Institutions 2
- Added 24 Jun 2016
- Updated 27 Oct 2026
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Comparison of Sequencing Platforms for Single Nucleotide Variant Calls in a Human Sample
Article 2013 EN Gold
Next-generation sequencings platforms coupled with advanced bioinformatic tools enable re-sequencing of the human genome at high-speed and large cost savings. We compare sequencing platforms from Roche/454(GS FLX), Illumina/HiSeq (HiSeq 2000), and Life Technologies/SOLiD (SOLiD 3 ECC) for their ability to identify single nucleotide substitutions in whole genome sequences from the same human sample…
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8.31
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6 authors| # | Author | Institutions | ORCID |
|---|---|---|---|
| 1 | Aakrosh Ratan | Pennsylvania State University (US) | |
| 2 | Webb Miller | Pennsylvania State University (US) | — |
| 3 | Joseph Guillory | Genentech (US) | — |
| 4 | Jeremy Stinson | Genentech (US) | — |
| 5 | Somasekar Seshagiri | Genentech (US) | |
| 6 | Stephan Christoph Schuster Corresponding | Pennsylvania State University (US) |
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